Patrick Scott, O.D., Ph.D.
Department of Ophthalmology & Visual Sciences
301 E. Muhammad Ali Boulevard,
Louisville KY 40202 Telephone: 502-852-1632
The New England College of Optometry, Boston, Massachusetts – 2006
Boston University School of Medicine, Boston, Massachusetts - 2011
Boston University School of Medicine, Boston, Massachusetts - 2007
My research is focused on retinal remodeling in animal models of retinal degeneration such as age-related macular degeneration and retinitis pigmentosa, as well as intervention therapies for rescuing photoreceptors in the wet-form of age-related maculopathy and inherited retinal degeneration.
Overby D.R., Hofmann S., Folz S., Kasper S.A., Lu Z., Scott P.A., and Gong H., 2006. Relationship between the hydrodynamic patterns of aqueous humor outflow and outflow resistance. Proceedings of the 5th World Congress of Biomechanics. 541-545. Munich, Germany.
Scott P.A., Overby D.R., Freddo T.F., Gong H., 2007. Comparative studies between species that do and do not exhibit the washout effect. Exp. Eye Res. 84, 435-443.
Lu Z., Overby D.R., Scott, P.A., Freddo T.F., Gong H. 2008. The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes. Exp. Eye Res. 86, 271-281.
Scott, P.A., Lu, Z., Liu, Y., Gong, H., 2009. Relationships between increased aqueous outflow facility during washout with changes in hydrodynamic pattern and morphology in bovine aqueous outflow pathways. Exp. Eye Res. 89, 942-949.
Scott, P.A., Kaplan, H.J., Sandell, J.H., 2011. Anatomical evidence of photoreceptor degeneration induced by iodoacetic acid in the porcine eye. Exp. Eye Res. 93, 513-527.
Noel, J.N., Demarco, P.J., Franco, L.M., Wang, W., Peng, X., Sandell, J.H., Scott, P.A., Kaplan, H.J., McCall, M.A., 2011. Iodoacetic acid, but not sodium iodate, creates an inducible model of retinal degeneration. Exp. Eye Res. 97, 137-147.
Umazume, K., Liu, L., Scott, P.A., Fernandez de Castro, J.P., McDonald, K., Kaplan, H.J., Tamiya, S., 2012. Assessment of tyrosine kinase inhibitor dasatinib as an adjunctive treatment for preventing PVR using in vitro assays and an in vivo swine model. (Submitted to IOVS).